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From Incurable to Preventable, the Success Story of Cancer of the Uterine Cervix

Received: 5 July 2022     Accepted: 20 July 2022     Published: 28 July 2022
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Abstract

Background: Until late 19th century, cancer of the uterine cervix was deemed incurable due to lack of effective treatment. With the introduction of anesthesia and disinfection surgical management was dared. Around 1895 Professor Wertheim of Vienna, introduced his technique of radical hysterectomy. Around that time X-rays was discovered in 1895 and radium in 1898. Both surgery and radiation therapy became available for the treatment of cervical cancer. Objective: Although in time both surgery and radiation therapy evolved with technical refinement as effective treatment, yet the major impact was in early diagnosis with the introduction of the pap smear cytology. More recently, the discovery of the relationship between human papilloma virus infection and cancer of the uterine cervix resulted in the development of an effective vaccine for preventing the disease. Conclusion: HPV vaccination has almost successfully prevented cancer of the uterine cervix in younger women.

Published in Journal of Gynecology and Obstetrics (Volume 10, Issue 4)
DOI 10.11648/j.jgo.20221004.13
Page(s) 183-185
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Cancer of the Uterine Cervix, Hysterectomy, Human Papilloma Virus, Radiotherapy, Cancer Prevention

References
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[2] Milena Falcaro, Alejandra Castanon, et al. The effects of the national HPV vaccination program in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence; a register-based observation study. The Lancet, vol. 398, issue 10316, p 2084-2092, December 04, 2021.
[3] Joseph Lister, On the antiseptic principle in the practice of surgery. Brit. Med. J., vol. 2, No. 351, pp 246-248, Sept. 21, 1867.
[4] Freund, W. A. Zu meiner methode der totalen Uterus-Extirpation. Centralbl. f. Gynak., 1878, Vol. ii, p. 265.
[5] Schuchardt, K. Eine neue methode der Gebarmutterextirpation. Centralblat. f. Chirurgie, 1893, vol xx, p. 1121.
[6] Schauta, F. Die operattion des Gebarmutterkrebses mittels des Schuchardt’schen Paravaginalschnittes. Monatschr. f. geburtsh. u. Gynak. 15: 133, 1902.
[7] Wertheim, E. A discussion on the diagnosis and treatment of cancer of the uterus. Proceedings of section of Obstetrics and Gynecology, British Medical Association, July 1905.
[8] Caldwell, E. W. Reported by Fredric Fluhman, The cervix uteri and its diseases. W. B. Saunders Co, Philadelphia, 1961, p. 362.
[9] Zowers, Z. T. The uses of radium. Correspondence between Z, T, Zowers and Alexander Graham Bell. American Med., 1903, 6, 261.
[10] Margret, Cleaves. Radium therapy. Med. Record, 1903, 64, 601-606.
[11] Dominici, H. De l’ulization de rayonnement et du radium en therapeutique. Congres Francois de Medicine IX, Paris 1907, 429-431.
[12] Chiron et R. Duval. Le traitment des canceres inoperable du col de l’uterus et vagin par l’utilisation massive du rayonement ultra-penetrant du radium. L’obst. 728, 1910.
[13] Abbe, R. The use of radium in malignant disease. The lancet, 1913, 2, 524-527.
[14] Forsell, G. Erfarenheter om radiumbehandeling av underlivskrafsa vid radiumhemmet, Stockholm 1910-1913, Hygiea 76, 1914.
[15] Lacassagne, A. La radiotherapie des epitheliomas du col uterin a l’Institut du Radium, Paris. Arch. De l’Inst. du Radium, 1930, 2, 95-132.
[16] Heyman, J. Radiological or operative treament of cancer of the uterus. Acta radiologica, 1927, 8, 363-409.
[17] Tod, M. C., Meredith, W. J. A dosage system for use in the treatment of cancer of the uterine cervix. B. J. Radiol. 1938, 11, 809.
[18] Meigs, J. V. Carcinoma of the cervix. New England J. Med. 230: 577-582, 607-613, 1944.
[19] Henschke, U. K. After loading application for the radium therapy of carcinoma of the uterus. Radiology, 74: 834, 1960.
[20] Williams, I. G., Kazem, I. High voltage X-ray therapy as a primary method of treatment for advanced cancer of the cervix uteri. B. J. R., 35: 18-22, January 1962.
[21] Kazem, I. Treatment of carcinoma of the uterine cervix. Refresher course, Radiological Society of North America annual meeting, Chicago, Ill., November 10, 1970.
[22] Rigoni-Stern. Fatti statisti relativi alle mallatie cancerose. Giorn. Prog. Patol. Terap., 2, 507-517, 1842.
[23] Hinselmann, H. Verbesserung der inspektionsmoglichkeit von Vulva, Vagina und Portio. Munchner Medizinische Wochochenschrift., 1925, 77: 1733.
[24] Papanicolaou, G., Traut, H. The diagnostic value of vaginal smears in carcinoma of the uterus. American J. of Obst. And Gynec., 42, 2, 193 – 206, August 1941.
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Cite This Article
  • APA Style

    Ismail Kazem. (2022). From Incurable to Preventable, the Success Story of Cancer of the Uterine Cervix. Journal of Gynecology and Obstetrics, 10(4), 183-185. https://doi.org/10.11648/j.jgo.20221004.13

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    ACS Style

    Ismail Kazem. From Incurable to Preventable, the Success Story of Cancer of the Uterine Cervix. J. Gynecol. Obstet. 2022, 10(4), 183-185. doi: 10.11648/j.jgo.20221004.13

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    AMA Style

    Ismail Kazem. From Incurable to Preventable, the Success Story of Cancer of the Uterine Cervix. J Gynecol Obstet. 2022;10(4):183-185. doi: 10.11648/j.jgo.20221004.13

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  • @article{10.11648/j.jgo.20221004.13,
      author = {Ismail Kazem},
      title = {From Incurable to Preventable, the Success Story of Cancer of the Uterine Cervix},
      journal = {Journal of Gynecology and Obstetrics},
      volume = {10},
      number = {4},
      pages = {183-185},
      doi = {10.11648/j.jgo.20221004.13},
      url = {https://doi.org/10.11648/j.jgo.20221004.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20221004.13},
      abstract = {Background: Until late 19th century, cancer of the uterine cervix was deemed incurable due to lack of effective treatment. With the introduction of anesthesia and disinfection surgical management was dared. Around 1895 Professor Wertheim of Vienna, introduced his technique of radical hysterectomy. Around that time X-rays was discovered in 1895 and radium in 1898. Both surgery and radiation therapy became available for the treatment of cervical cancer. Objective: Although in time both surgery and radiation therapy evolved with technical refinement as effective treatment, yet the major impact was in early diagnosis with the introduction of the pap smear cytology. More recently, the discovery of the relationship between human papilloma virus infection and cancer of the uterine cervix resulted in the development of an effective vaccine for preventing the disease. Conclusion: HPV vaccination has almost successfully prevented cancer of the uterine cervix in younger women.},
     year = {2022}
    }
    

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    AB  - Background: Until late 19th century, cancer of the uterine cervix was deemed incurable due to lack of effective treatment. With the introduction of anesthesia and disinfection surgical management was dared. Around 1895 Professor Wertheim of Vienna, introduced his technique of radical hysterectomy. Around that time X-rays was discovered in 1895 and radium in 1898. Both surgery and radiation therapy became available for the treatment of cervical cancer. Objective: Although in time both surgery and radiation therapy evolved with technical refinement as effective treatment, yet the major impact was in early diagnosis with the introduction of the pap smear cytology. More recently, the discovery of the relationship between human papilloma virus infection and cancer of the uterine cervix resulted in the development of an effective vaccine for preventing the disease. Conclusion: HPV vaccination has almost successfully prevented cancer of the uterine cervix in younger women.
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Author Information
  • College of Medicine, University of South Florida, Tampa, Florida

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